Multiple Sclerosis (MS) is a chronic neurological condition which is more common in women than men, and is commonly diagnosed in patients who are of a younger age (NICE 2024). Many women with MS are of childbearing age and may want to have children.
It is safe to become pregnant if you have MS, but it is recommended that you seek advice and make plans with your MS team before becoming pregnant where possible. This is because some Disease Modifying Treatments (DMTs) can carry risk in pregnancy. Planning your pregnancy can help reduce your risks of long-term disability and ensure the best outcomes for both you and your baby.
If you do wish to become pregnant, it is important that you discuss with your MS team before trying to conceive. This is because some of your medications, including your DMT, may need adjustment before conception and pregnancy. If you are pregnant and have not made plans with your MS team, it’s important that you contact them as soon as possible. Depending on your medication, this might need to be stopped or changed to a better and safer treatment for pregnancy. Plans for your birth and feeding choices will be made between you and your team. If you want to breastfeed, this will be part of decisions made around medications and treatment.
Symptom management medications used to manage any symptoms related to your MS should also be discussed with your MS team and your midwife, as some medicines should not be taken when trying to conceive or during pregnancy. Where possible, we will discuss safer alternatives, as well as the evidence available about safety, to help you to make informed decisions.
There is evidence to suggest women are more protected against relapses during pregnancy, with some evidence suggesting an increased risk for relapses in the postnatal period; However, this also depends on how stable your MS is leading up to your pregnancy—the more stable you are, the less risk for relapses during pregnancy.
The studies linked earlier in this information suggest that women are more protected against relapses during pregnancy, with an increased risk for relapses in the post-partum period.
However, some MS symptoms can become worse during pregnancy, especially fatigue and bladder symptoms, due to the overlapping symptoms of pregnancy and MS.
To manage your MS symptoms during pregnancy:
If you have concern regarding new and increase in symptoms, please discuss with your care team.
Remember overall the outlook for you and your baby during pregnancy is very good.
For further advice and support, contact your MS nurse. More information can be found on the following websites:
Your healthcare team is here to support you through your pregnancy journey, ensuring both your health and the health of your baby.
